#UMED-TECH-001
SUMMARY
The subject matter of the invention is a pharmaceutical composition for topical application containing a beta- adrenergic receptor antagonist and a corticosteroid and use thereof in the treatment of hemangiomas in children.
BACKGROUND
Current clinical observations indicate that haemangiomas occur in about 10% of infants. They have a pronounced clinical course that can lead to the development of tumour-like lesions in up to 76% of children by the age of seven.
There are currently several treatment options for haemangiomas. One commonly used approach is the oral administration of cardiac drugs, which accelerate the regression of the vascular lesions and often lead to their complete disappearance. The efficacy of these drugs in the treatment of haemangiomas was discovered incidentally, but due to their high efficacy, this therapy is now routinely used worldwide according to established treatment standards. However, a significant disadvantage of this method is that hospitalisation, an ECG examination and a cardiological consultation are required before treatment can begin.
The innovation presented in this application lies in a new formulation and route of administration for cardiac drugs. By delivering the active substance in a topical form, the need for hospitalisation and diagnosis prior to treatment can be eliminated.
FEATURES AND KEY BENEFITS
- Safety – Use of a known and clinically validated active pharmaceutical ingredient (API) with an established safety profile.
- No need for hospitalisation and diagnostic qualification.
- Ease of use – topical application without professional supervision.
- First class solution – there are currently no other products with this indication and route of administration.
- IP protected – the invention is protected by a patent already granted in Poland and the procedure for extending protection via the European Patent Office (EPO) is currently underway.
REFERENCES
Pat.244294 https://ewyszukiwarka.pue.uprp.gov.pl/search/pwp-details/P.442316
PCT patent application PCT/PL2023/050078 – https://www.wipo.int/search/en/results?q=PCT%2FPL2023%2F050078
AVAILABLE
for licensing
CONTACT
Medical University of Łódź, The Center for Innovation and Technology Transfer Ciitt@umed.lodz.pl
